Research Sequencing
Research Sequencing
The New York Genome Center (NYGC)’s strategic direction is to drive genomic discovery in neurological diseases and cancer.
Our Mission
Our mission is to apply our strengths in whole genome sequencing, RNA sequencing, single-cell sequencing, state-of-the-art analytics, and the development of new genetic tools to further genomic research. Through our research and collaborations we aim to support scientific advances leading to new insights for the benefit of patients with neurodegenerative diseases, neuropsychiatric diseases, and cancer.
Our standard protocols include:
- Short read whole genome sequencing
- Transcriptomic and total RNA sequencing
- Lane sequencing of prepared library pools
- Single cell and single nuclei sequencing
- Long read sequencing
Disease Focus Areas
We support three disease-research areas with our ongoing commitment to technology innovation, particularly in single-cell and spatial transcriptomics. This includes our computational analysis of genomic and transcriptomic data, population-level statistical analyses, and the integration of diverse data sets.
We also support large-scale population genomic projects outside of our focused disease areas.
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Neurodegenerative Diseases
Leveraging the success of our international consortium for ALS research to extend our work across a range of neurodegenerative diseases that have pathways in common with ALS (such as Alzheimer’s, Parkinson’s, and Huntington’s).
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Neuropsychiatric Diseases
Expanding our research of whole genomes of autism patients into a range of related disorders, such as schizophrenia and bipolar, that have genes implicated in common with autism.
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Cancer
Pushing forward the leading edge of cancer genomics research by focusing on whole genome sequencing of individuals with cancer and their tumors, novel population-level cancer analytics, and the application of both single cell and spatial transcriptomics.
Contact Us
Please contact our project management team with any questions about projects, collaborations, grants, or other ways to become engaged with the NYGC.
