Our Scientific Publications
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bioRxiv · September 22, 2024 · Preprint
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Muscle & Nerve · September 18, 2024
Access for ALL in ALS: A large-scale, inclusive, collaborative consortium to unlock the molecular and genetic mechanisms of amyotrophic lateral sclerosis.
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Cold Spring Harbor Perspectives in Biology · September 16, 2024
Glia in Neurodegenerative Disease.
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American Society of Human Genetics · September 12, 2024
Semi-supervised machine learning method for predicting homogeneous ancestry groups to assess Hardy-Weinberg equilibrium in diverse whole-genome sequencing studies.
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Nature Medicine · September 3, 2024
A framework for sharing of clinical and genetic data for precision medicine applications.
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Alzheimer's & Dementia · August 30, 2024
Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer’s disease and older controls in multi-ethnic populations.
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bioRxiv · August 27, 2024 · Preprint
Type 1 interferon perturbates clonal competition by reshaping human blood development.
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bioRxiv · August 19, 2024 · Preprint
DeepSomatic: Accurate somatic small variant discovery for multiple sequencing technologies.
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Cell Reports · August 16, 2024
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes.
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Cell · August 8, 2024
Multiplexed single-cell characterization of alternative polyadenylation regulators.
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Muscle & Nerve · August 9, 2024
Mitochondrial genome variants associated with amyotrophic lateral sclerosis and their haplogroup distribution.
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Nature Communications · August 8, 2024
Multi-omic analysis of Huntington’s disease reveals a compensatory astrocyte state.
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Scientific Reports · August 1, 2024
A methylation risk score for chronic kidney disease: a HyperGEN study.
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bioRxiv · July 19, 2024 · Preprint
ALS molecular subtypes are a combination of cellular, genetic, and pathological features learned by deep multiomics classifiers.
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Genome Biology · July 18, 2024
Leveraging neighborhood representations of single-cell data to achieve sensitive DE testing with miloDE.
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American Journal of Human Genetics · July 11, 2024
The DARC side of genetics in cancer: Breast cancer disparities.
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The EMBO Journal · July 1, 2024
YTHDC1 m6A-dependent and m6A-independent functions converge to preserve the DNA damage response.
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Chest Journal · June 28, 2024
Clinical Impact of Telomere Length Testing for Interstitial Lung Disease.
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BMC Genomics · June 29, 2024
Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS.
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Journal of Biomedical Informatics · June 25, 2024
Privacy-preserving model evaluation for logistic and linear regression using homomorphically encrypted genotype data.
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Bioinformatics · June 20, 2024
SEraster: a rasterization preprocessing framework for scalable spatial omics data analysis.