Our Scientific Publications
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Genome Biology · December 18, 2024
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medRxiv · December 8, 2024 · Preprint
Epigenome-wide Association Analysis of Mitochondrial Heteroplasmy Provides Insight into Molecular Mechanisms of Disease.
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medRxiv · December 13, 2024 · Preprint
Deriving Mendelian Randomization-based Causal Networks of Brain Imaging Phenotypes and Bipolar Disorder.
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medRxiv · December 8, 2024 · Preprint
Leveraging functional annotations to map rare variants associated with Alzheimer’s disease with gruyere.
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American Journal of Human Genetics · December 5, 2024
Employing effective recruitment and retention strategies to engage a diverse pediatric population in genomics research.
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Genome Research · December 5, 2024
An integrative TAD catalog in lymphoblastoid cell lines discloses the functional impact of deletions and insertions in human genomes.
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BMC Cancer · December 2, 2024
Patterns of breast cancer locoregional relapse, metastasis, and subtypes in Ghana.
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Science · November 28, 2024
A panoramic view of cell population dynamics in mammalian aging.
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bioRxiv · November 27, 2024 · Preprint
Paired CRISPR screens to map gene regulation in cis and trans.
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Nature Biotechnology · November 21, 2024
Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling.
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Nature Genetics · November 20, 2024
Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations.
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bioRxiv · November 14, 2024 · Preprint
Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord.
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Computational Biology and Chemistry · November 16, 2024
Vector embeddings by sequence similarity and context for improved compression, similarity search, clustering, organization, and manipulation of cDNA libraries.
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Cell · November 14, 2024
From bacterial operons to gene therapy: 50 years of the journal Cell.
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Alzheimer's & Dementia · November 13, 2024
Large-scale deep proteomic analysis in Alzheimer’s disease brain regions across race and ethnicity.
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Genetics in Medicine · November 12, 2024
Upregulation vs. loss of function of NTRK2 in 44 affected individuals leads to two distinct neurodevelopmental disorders.
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Cell · November 7, 2024
Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells.
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Nature · October 30, 2024
RAS-mutant leukaemia stem cells drive clinical resistance to venetoclax.
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bioRxiv · October 17, 2024 · Preprint
An analysis of RNA quality metrics in human brain tissue.
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bioRxiv · October 16, 2024 · Preprint
A Reproducibility Focused Meta-Analysis Method for Single-Cell Transcriptomic Case-Control Studies Uncovers Robust Differentially Expressed Genes.
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bioRxiv · October 15, 2024 · Preprint
Efficient indexing and querying of annotations in a pangenome graph.